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Comparative Analysis of Metabolic Differences of Jersey Cattle in Different High-Altitude Areas

文献类型： 外文期刊

作者： Kong, Zhiwei 1 ; Li, Bin 4 ; Zhou, Chuanshe 5 ; He, Qinghua 1 ; Zheng, Yuzhong 3 ; Tan, Zhiliang 5 ;

作者机构： 1.Shenzhen Univ, Coll Chem & Environm Engn, Dept Food Sci & Engn, Shenzhen, Peoples R China

2.Shenzhen Univ, Key Lab Optoelect Devices & Syst, Minist Educ & Guangdong Prov, Coll Optoelect Engn, Shenzhen, Peoples R China

3.Hanshan Nornal Univ, Sch Food Engn & Biotechnol, Chaozhou, Peoples R China

4.Tibet Autonomous Reg Acad Agr Sci, Inst Anim Husb & Vet, State Key Lab Hulless Barley & Yak Germplasm Reso, Lhasa, Peoples R China

5.Chinese Acad Sci, Inst Subtrop Agr, CAS Key Lab Agroecol Proc Subtrop Reg,Natl Engn L, Hunan Prov Key Lab Anim Nutr Physiol & Metab Proc, Changsha, Peoples R China

关键词： metabonomics; high altitude; Jersey cattle; difference; hypoxia

期刊名称：FRONTIERS IN VETERINARY SCIENCE （ 影响因子：3.471； 五年影响因子：3.821 ）

ISSN：

年卷期： 2021 年 8 卷

页码：

收录情况： SCI

摘要： In high-altitude area, hypoxia is a serious stress for humans and other animals, disrupting oxygen homeostasis and thus affecting tissue metabolism. Up to now, there are few reports on the metabolic changes of dairy cows at different altitudes. In this experiment, metabonomics technology and blood biochemical indexes were used to study the metabolic changes of dairy cows in different altitudes. The results showed that the different metabolites were mainly enriched in amino acid metabolism and sphingolipid metabolism, and sphingolipid metabolism showed a negative correlation with increased altitude. The results of this study will enrich the hypoxia-adaptive mechanism of dairy cows in high-altitude areas and provide a theoretical basis for the nutritional regulation of performance and disease treatment of dairy cows in high-altitude areas.

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