Taxonomic and functional adaption of the gastrointestinal microbiome of goats kept at high altitude (4800 m) under intensive or extensive rearing conditions
文献类型： 外文期刊
作者： Zhang, Ke 1 ; He, Chong 2 ; Xu, Yangbin 1 ; Zhang, Chenguang 1 ; Li, Chao 1 ; Jing, Xu 2 ; Wang, Meili 2 ; Yang, Yuxin 1 ; S 1 ;
作者机构： 1.Northwest A&F Univ, Coll Anim Sci & Technol, Key Lab Anim Genet Breeding & Reprod Shaanxi Prov, Yangling 712100, Shaanxi, Peoples R China
2.Northwest A&F Univ, Coll Informat Engn, Yangling 712100, Shaanxi, Peoples R China
3.Tibet Acad Agr & Anim Husb Sci, Inst Anim Sci, Lhasa 850009, Peoples R China
4.Univ Maryland, Dept Anim & Avian Sci, College Pk, MD 20742 USA
5.Univ Zurich, Vet Fac, Inst Anim Nutr, CH-8057 Zurich, Switzerland
关键词： microbiome; rumen; hindgut; grazing; goats; highland adaptation
期刊名称：FEMS MICROBIOLOGY ECOLOGY （ 影响因子：3.675； 五年影响因子：4.562 ）
ISSN： 0168-6496
年卷期： 2021 年 97 卷 3 期
页码：
收录情况： SCI
摘要： The gut microbiota composition is influenced by the diet as well as the environment in both wild and domestic animals. We studied the effects of two feeding systems on the rumen and hindgut microbiome of semi-feral Tibetan goats kept at high altitude (similar to 4800 m) using 16S rRNA gene and metagenomic sequencing. Intensive drylot feeding resulted in significantly higher zootechnical performance, narrower ruminal acetate: propionate ratios and a drop in the average rumen pH at slaughter to similar to 5.04. Hindgut microbial adaption appeared to be more diverse in the drylot group suggesting a higher influx of undegraded complex non-starch polysaccharides from the rumen. Despite their higher fiber levels in the diet, grazing goats exhibited lower counts of Methanobrevibacter and genes associated with the hydrogenotrophic methanogenesis pathway, presumably reflecting the scarce dietary conditions (low energy density) when rearing goats on pasture from extreme alpine environments. These conditions appeared to promote a relevant abundance of bacitracin genes. In parallel, we recognized a significant increase in the abundance of antibiotic resistance genes in the digestive tracts of drylot animals. In summary, this study provides a deeper insight into the metataxonomic and functional adaption of the gastrointestinal microbiome of goats subject to intensive drylot and extensive pasture rearing conditions at high altitude.
- 相关文献
作者其他论文 更多>>
-
The Role of miR-326-3p in Regulating Differentiation and Thermogenesis Genes in Goat Brown Adipocytes
作者：Zhu, Yuehua;Jiang, Tingting;Jiang, Xinyi;Xia, Yanyan;Wang, Linjie;Zhu, Yuehua;Jiang, Tingting;Jiang, Xinyi;Xia, Yanyan;Wang, Linjie;Suo, Langda
关键词：miR-326-3p; brown adipocytes; goat; FGF11
-
Compendium of 5810 genomes of sheep and goat gut microbiomes provides new insights into the glycan and mucin utilization
作者：Zhang, Ke;Zhang, Ting;Xu, Yangbin;Lei, Yu;Liu, Gongwei;Qian, Quan;Mao, Yunrui;Kalds, Peter;Yang, Yuxin;Wang, Xiaolong;Chen, Yulin;He, Chong;Wang, Meili;Wang, Lei;Suo, Langda;Wu, Yujiang;Cuoji, Awang;Suo, Langda;Wu, Yujiang;Cuoji, Awang;Guo, Mengmeng;Guo, Jiazhong;Brugger, Daniel;Gan, Shangquan;Wang, Xiaolong;Chen, Yulin;Wang, Xiaolong;Chen, Yulin;Zhao, Fangqing
关键词：
-
Multi-omic Analyses Shed Light on The Genetic Control of High-altitude Adaptation in Sheep
作者：Li, Chao;Chen, Bingchun;Zhou, Shiwei;Kalds, Peter;Zhang, Ke;Huang, Shuhong;Li, Ran;Li, Yan;Fang, Wenwen;Cai, Yudong;Jiang, Yu;Chen, Yulin;Wang, Xiaolong;Li, Chao;Bhati, Meenu;Leonard, Alexander;Pausch, Hubert;Langda, Suo;Cuoji, Awang;Wu, Yujiang;Cuomu, Renqin;Gui, Ba;Pu, Peng;Zhu, Xiaojia;Wang, Xiran;Zhu, Haolin;Li, Ming;Wang, Yutao;Jia, Ting;Pu, Tianchun;Pan, Xiangyu;He, Chong;Zhou, Ping;Zhou, Ping;Han, Jian-Lin;Han, Jian-Lin
关键词：Environmental adaptation; High altitude; Hypoxia; Selection signature; Sheep
-
Age-specific composition of milk microbiota in Tibetan sheep and goats
作者：Cao, Xi;Fang, Yumeng;Chen, Yulin;Zhang, Ke;Bandan, Pingcuo;Suo, Langda;Jiacuo, Gesang;Wu, Yujiang;Cuoji, Awang;Zhuoga, Deqing;Ji, De;Quzhen, Ciren
关键词：Milk microbiota; Ruminant; Colostrum; Milk composition; Lactobacillus
-
circRNA3669 promotes goat endometrial epithelial cells proliferation via miR-26a/ RCN2 to activate PI3K/AKT-mTOR and MAPK pathways
作者：Liu, Xiaorui;Zhou, Min;Cui, Jiuzeng;Wei, Mengyao;Wang, Xiaofei;Liu, Yuexia;Zhu, Zhongshi;Song, Yuxuan;Zhang, Lei;Ba, Gui;Suo, Langda
关键词：circRNA3669; RCN2; miR-26a; goat endometrial epithelial cells (GEECs); proliferation
-
Genome-wide association analysis of fleece traits in Northwest Xizang white cashmere goat
作者：Lu, Xiaotian;Suo, Langda;Ji, De;Cuomu, Renqing;Cuoji, Awang;Gui, Ba;Wu, Yujiang;Lu, Xiaotian;Yan, Xiaochun;Li, Wenze;Su, Yixin;Zhou, Bohan;Liu, Can;Yang, Lepu;Wang, Jiayin;Wang, Zhiying;Jiang, Wei;Su, Rui;Ji, De;Cuomu, Renqing;Cuoji, Awang;Gui, Ba;Wu, Yujiang;Su, Rui
关键词：Northwest Xizang white cashmere goat; genome-wide association analysis; cashmere trait; GGP_Goat_70K SNP chip; linear mixed model; Sanger sequencing
-
Stress adaptation in Tibetan cashmere goats is governed by inherent metabolic differences and manifested through variable cashmere phenotypes
作者：Zhao, Bingru;Zhao, Bingru;Chen, Tong;Tulafu, Hanikezi;Lu, Qingwei;Liu, Wenna;Fu, Xuefeng;Suo, Langda;Wu, Yujiang;Lu, Qingwei;Liu, Wenna;Sammad, Abdul;Wu, Cuiling
关键词：Tibetan cashmere goat; Stress adaptation; Metabolite; Multi-omics analysis; KEGG pathways
